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What can I expect going from Effexor XR 75mg to. i have been on effexor xr, 150 mg for about 5 years or so. and one thing that i can tell you is.Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr.Buying Effexor XR 150 mg from the CanAmerican Global pharmacy is often cheaper than from US retail outlets.